Do you need more information
Do you need more information
Parechoviruses may be responsible for severe diseases such as encephalitis and meningitis. Optimized detection of Parechovirus infection is therefore very important and Parechovirus R-GENE®, offering rapid and specific detection, is an ideal solution.
*Coming soon
The Parechovirus R-GENE® kit is a ready-to-use molecular detection kit. It enables the detection of Parechoviruses using real-time PCR after viral RNA extraction on CSF samples. It works by amplifying and simultaneously detecting a specific region of the Parechovirus genome using 5’ nuclease Taqman technology.
Using the Parechovirus R-GENE® kit is easy. Just add the extracted RNA sample to your PCR master mix and start the reaction on the appropriate Real-Time PCR thermocycler, following optimized cycling program described in the “Instructions For Use”.
BIOMERIEUX, the blue logo, ARGENE®, R-GENE®, EASYMAG® and NUCLISENS® are used, pending and/or registered trademarks belonging to bioMérieux, or one of its subsidiaries, or one of its companies. Any other name or trademark is the property of its respective owner.
Parechovirus R-GENE® (71-020) | |
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Principle of the test | Genomic detection of Parechovirus |
Ordering information | Reference 71-020: Parechovirus R-GENE® |
Technology | Real-Time PCR / 5‘ nuclease Taqman technology |
Gene target | 5‘ UTR region |
Specimen* | CSF |
Controls included | Extraction + Inhibition control, Positive control, Negative control |
Results within | 90 minutes (extraction step not included) |
Number of tests | 60 tests |
Storage conditions | -18°C/-22°C |
Validated Extraction platform* Automated | NUCLISENS® EASYMAG® MagNA Pure Compact |
Validated Amplification platform* | Life Technologies (ABI7500 Fast) LightCycler 480 System II RotorGene Bio-Rad DX Real-Time system |
Status | For in vitro diagnostic use, CE marking in Europe |
* please enquire
What is Parechovirus?
Members of the Picornaviridae family, Parechoviruses are single-strand RNA viruses, split into 2 species (Human parechovirus and Ljungan virus). Sixteen genotypes of Human Parechoviruses have been identified so far. Human parechoviruses are common pathogens as a seroprevalence of 95% has been reported. Human Parechoviruses are usually asymptomatic or cause mild respiratory or gastrointestinal manifestations. However, Human Parechoviruses have also been described to be associated with serious respiratory illnesses, encephalitis and aseptic meningitis. They are suspected to be the 2nd most frequent viral cause of sepsis-like and meningitis after Enteroviruses.
Who is most at risk?
Children less than 5 years old are the most at risk of becoming ill.
What are the benefits of Parechoviruses molecular testing?
Real-Time PCR-based assays enable rapid and sensitive detection of human Parechovirus (HPeV) to help improve patient management.